Reflecting to optimise

Software Development, AI & Machine Learning(magnusross.github.io)view on HackerNews

optimizationprotein binder designprojected gradient descentmirror descentKL divergence

Author: magni121

Date: 6/26/2026

Article Summary:

The article discusses the author's experience with optimizing a protein binder design problem and their exploration of different optimization methods, including projected gradient descent (PGD) and mirror descent.